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1 Indications And Usage Repatha Is A Pcsk9 (Proprotein Convertase Subtilisin Kexin Type 9) Inhibitor Antibody Indicated: To Reduce The Risk Of Myocardial Infarction, Stroke, And Coronary Revascularization In Adults With Established Cardiovascular Disease. ( 1.1 ) As An Adjunct To Diet, Alone Or In Combination With Other Lipid-Lowering Therapies (E.g., Statins, Ezetimibe), For Treatment Of Adults With Primary Hyperlipidemia (Including Heterozygous Familial Hypercholesterolemia [Hefh]) To Reduce Low-Density Lipoprotein Cholesterol (Ldl-C). ( 1.2 ) As An Adjunct To Diet And Other Ldl-Lowering Therapies (E.g., Statins, Ezetimibe, Ldl Apheresis) In Patients With Homozygous Familial Hypercholesterolemia (Hofh) Who Require Additional Lowering Of Ldl-C. ( 1.3 ) 1.1 Prevention Of Cardiovascular Events In Adults With Established Cardiovascular Disease, Repatha Is Indicated To Reduce The Risk Of Myocardial Infarction, Stroke, And Coronary Revascularization. 1.2 Primary Hyperlipidemia (Including Heterozygous Familial Hypercholesterolemia [Hefh]) Repatha Is Indicated As An Adjunct To Diet, Alone Or In Combination With Other Lipid-Lowering Therapies (E.g., Statins, Ezetimibe), For The Treatment Of Adults With Primary Hyperlipidemia To Reduce Low-Density Lipoprotein Cholesterol (Ldl-C). 1.3 Homozygous Familial Hypercholesterolemia (Hofh) Repatha Is Indicated As An Adjunct To Diet And Other Ldl-Lowering Therapies (E.g., Statins, Ezetimibe, Ldl Apheresis) For The Treatment Of Patients With Hofh Who Require Additional Lowering Of Ldl-C.
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