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1 Indications And Usage Indomethacin For Injection Is Indicated To Close A Hemodynamically Significant Patent Ductus Arteriosus In Premature Infants Weighing Between 500 And 1,750 G When 48 Hours Usual Medical Management (E.g., Fluid Restriction, Diuretics, Digitalis, Respiratory Support, Etc.) Is Ineffective. Clear-Cut Clinical Evidence Of A Hemodynamically Significant Patent Ductus Arteriosus Should Be Present, Such As Respiratory Distress, A Continuous Murmur, A Hyperactive Precordium, Cardiomegaly, Or Pulmonary Plethora On Chest X-Ray. Indomethacin For Injection Is A Cardiovascular Drug Indicated: To Close A Hemodynamically Significant Patent Ductus Arteriosus In Premature Infants Weighing Between 500 And 1,750 G. ( 1 )
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