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Indications And Usage Women Gonal-F ® (Follitropin Alfa For Injection) Is Indicated For The Induction Of Ovulation And Pregnancy In The Anovulatory Infertile Patient In Whom The Cause Of Infertility Is Functional And Not Due To Primary Ovarian Failure. Gonal-F ® Is Also Indicated For The Development Of Multiple Follicles In The Ovulatory Patient Participating In An Assisted Reproductive Technology (Art) Program. Selection Of Patients Before Treatment With Gonal-F ® Is Instituted, A Thorough Gynecologic And Endocrinologic Evaluation Must Be Performed. This Should Include An Assessment Of Pelvic Anatomy. Patients With Tubal Obstruction Should Receive Gonal-F ® Only If Enrolled In An In Vitro Fertilization Program. Primary Ovarian Failure Should Be Excluded By The Determination Of Gonadotropin Levels. Appropriate Evaluation Should Be Performed To Exclude Pregnancy. Patients In Later Reproductive Life Have A Greater Predisposition To Endometrial Carcinoma As Well As A Higher Incidence Of Anovulatory Disorders. A Thorough Diagnostic Evaluation Should Always Be Performed In Patients Who Demonstrate Abnormal Uterine Bleeding Or Other Signs Of Endometrial Abnormalities Before Starting Gonal-F ® Therapy. Evaluation Of The Partner's Fertility Potential Should Be Included In The Initial Evaluation. Men Gonal-F ® (Follitropin Alfa For Injection) Is Indicated For The Induction Of Spermatogenesis In Men With Primary And Secondary Hypogonadotropic Hypogonadism In Whom The Cause Of Infertility Is Not Due To Primary Testicular Failure. Selection Of Patients Before Treatment With Gonal-F ® Is Instituted For Azoospermia, A Thorough Medical And Endocrinologic Evaluation Must Be Performed. Hypogonadotropic Hypogonadism Should Be Confirmed, And Primary Testicular Failure Should Be Excluded By The Determination Of Gonadotropin Levels. Prior To Gonal-F ® Therapy For Azoospermia In Patients With Hypogonadotropic Hypogonadism, Serum Testosterone Levels Should Be Normalized.
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