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1 Indications And Usage Gemcitabine Is A Nucleoside Metabolic Inhibitor Indicated: In Combination With Carboplatin, For The Treatment Of Advanced Ovarian Cancer That Has Relapsed At Least 6 Months After Completion Of Platinum-Based Therapy. ( 1.1 ) In Combination With Paclitaxel, For First-Line Treatment Of Metastatic Breast Cancer After Failure Of Prior Anthracycline-Containing Adjuvant Chemotherapy, Unless Anthracyclines Were Clinically Contraindicated. ( 1.2 ) In Combination With Cisplatin, For The Treatment Of Non-Small Cell Lung Cancer. ( 1.3 ) As A Single Agent For The Treatment Of Pancreatic Cancer. ( 1.4 ) 1.1 Ovarian Cancer Gemcitabine In Combination With Carboplatin Is Indicated For The Treatment Of Patients With Advanced Ovarian Cancer That Has Relapsed At Least 6 Months After Completion Of Platinum-Based Therapy. 1.2 Breast Cancer Gemcitabine In Combination With Paclitaxel Is Indicated For The First-Line Treatment Of Patients With Metastatic Breast Cancer After Failure Of Prior Anthracycline-Containing Adjuvant Chemotherapy, Unless Anthracyclines Were Clinically Contraindicated. 1.3 Non-Small Cell Lung Cancer Gemcitabine In Combination With Cisplatin Is Indicated For The First-Line Treatment Of Patients With Inoperable, Locally Advanced (Stage Iiia Or Iiib) Or Metastatic (Stage Iv) Non-Small Cell Lung Cancer (Nsclc). 1.4 Pancreatic Cancer Gemcitabine Is Indicated As First-Line Treatment For Patients With Locally Advanced (Nonresectable Stage Ii Or Stage Iii) Or Metastatic (Stage Iv) Adenocarcinoma Of The Pancreas. Gemcitabine Is Indicated For Patients Previously Treated With Fluorouracil.
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